Clinically-Driven

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Putting the Pharmacist Back in Pharmacy Benefits Management

EmpiRx Health is transforming the PBM industry by putting the pharmacist at the center of a clinically-driven, customer-first pharmacy care model. Our clinical pharmacists use AI-powered population health analytics to coordinate the best patient care, producing better plan performance and customer results and optimizing member health outcomes. It’s a transformative PBM operating model that literally puts the pharmacist back in the center of pharmacy benefits management.

Holistically Evaluating Patients’ Needs

The EmpiRx Health clinically-driven PBM model holistically evaluates patients healthcare needs based on their own unique needs and risk factors. The pharmacist collaborates peer-to-peer with the patient’s prescribing physician to suggest clinically-appropriate changes to their drug therapies. This usually involves recommending lower-cost medications or dosing and regimen changes and optimizations.

EmpiRx Health’s clinically-driven pharmacy care model emphasizes value over volume. Unlike other PBMs, our pharmacy care approach does not rely on a restrictive formulary or reduced medication access to maximize rebates and drive inappropriate utilization of high-cost therapies. The EmpiRx Health clinically-driven PBM model relies on pharmacists collaborating with physicians and practitioners to produce the optimal drug mix that optimizes health outcomes while reducing costs.

Biosimilars Become an Increasingly Important Part of Pharmacy Care

During the past year, there has been a lot of buzz about biosimilars as lower-cost alternatives to biologic drugs. Biosimilars are biologic medications that are highly similar to drugs already approved by the FDA. They are used for treating the same conditions and have the same mechanism of action as the reference, or originator, products. Through clinical trials, biosimilars have been proven to be just as safe and effective as their reference biologic drugs, meeting the same quality standards.

There is a growing expectation that biosimilars will transform the specialty drug landscape just like generic drugs did for traditional medications. They can increase access to important therapies and improve patient outcomes, all while providing a lower-cost option for patients.

As the leading clinically-driven PBM company, EmpiRx Health has been an early adopter of biosimilars. Why? Because biosimilars offer the same level of safety and effectiveness as the original products, but at a lower cost – sometimes substantially lower. In fact, EmpiRx Health was one of the first PBMs that started to prefer lower cost biosimilars to original products.

Many other PBM companies are not prioritizing the lower cost biosimilars because doing so would run counter to their business models. These legacy PBM business models are fundamentally misaligned with the needs and interests of plan sponsors and their members.

In early 2023, EmpiRx Health was the only PBM that decided to prefer the lower cost Humira biosimilars in its formularies. Prior to making this decision, EmpiRx Health’s pharmacy experts performed a thorough review of available clinical data, dosing and formulation options, and other critical factors impacting member experience. Following that comprehensive review and analysis, we decided to select two of the lowest priced Humira biosimilars for our formulary.

This Humira formulary decision was consistent with our clinically-driven, customer-first pharmacy care approach, which puts the pharmacist at the center of the care model. When you put the pharmacist back in pharmacy benefits management, everyone wins.

Clinically-Driven Pharmacy Care at Work

WHOLE-PERSON HEALTHCARE
Patient: 57-year-old male
Diagnosis: Plaque Psoriasis
Original Rx: Cosentyx injection loading + maintenance dose
Population Health Management Engine Identified: High-cost specialty medication for a high-risk member
Our Clinical Pharmacist identified that the patient’s medical history was significant for diverticulosis. Recent literature indicates
Cosentyx may exacerbate symptoms of inflammatory bowel disease. Our pharmacist recommended Otezla, which is lower cost medication and won’t exacerbate inflammatory bowel disease.

  • New Therapy: Otezla Starter + maintenance dose
  • $21,068 Annual Plan Savings achieved.
DOSE OPTIMIZATION: PREVENTATIVE ACTION 
Patient: 59-year-old female
Diagnosis: ADHD
Original Rx: Vyvanse 50mg + 70mg daily 
Population Health Management Engine Identified: Potential drug-condition interaction for a high-risk member
Our Clinical Pharmacist identified the patient was taking several medications for mental health and chart notes revealed a history of alcohol abuse. The maximum dose recommendation of Vyvanse is 70mg, and in addition it can hide the effects of intoxication and raise the risk of alcohol poisoning. Our Clinical Pharmacist recommended adjusting the dose and monitoring the patient for alcohol abuse.

  • New Therapy: Vyvanse 70mg daily
  • Outcome: The patient has continued treatment with 70mg dose, with monthly follow ups by psychiatrist and plan to taper the dose down.
  • $6,715 Annual Plan Savings achieved

The Clinically-Driven PBM Model is Key to
Managing Specialty Drug Costs

It’s no secret that prescription drugs have become an increasingly large part of every dollar spent on healthcare. But only 1-2% of a patient population is driving around half of total prescription spending. That high level of drug spending is largely driven by patients utilizing specialty medications.
Specialty cost trends are increasing at a significantly higher rate than for traditional or non-specialty medications. Over the last few years, most new drugs approved by the FDA have been specialty. The drug pipeline is still predominantly focused on specialty medications. In the past year, there have been 55 specialty medications approved by the FDA. And there are almost 50 specialty medications already slated for FDA decisions in 2024.

The seemingly non-stop growth in specialty drug launches and the associated exploding costs put enormous pressure on plan sponsors and their members, who are also seeing rising premiums, higher deductibles, and growing copays or coinsurance.

EmpiRx Health’s value-based, clinically-driven pharmacy care model is made for the specialty drug challenge. Intimately involved with every client, our expert clinical pharmacists use the most sophisticated population health technologies to identify opportunities to mitigate the soaring costs of specialty drugs.

Here’s how: Our pharmacists collaborate peer-to-peer with the patient’s prescribing physician to suggest clinically-appropriate changes to their drug therapies. This involves recommending lower-cost medications or dosing and regimen optimizations.

This pharmacist-centric care model emphasizes value over volume. It doesn’t rely on a restrictive formulary or reduce medication access to maximize rebates and drive inappropriate utilization of high-cost therapies. The EmpiRx Health clinically-driven pharmacy care approach relies on pharmacists collaborating with physicians and practitioners to drive to the most appropriate and cost-effective drug mix that optimizes the health outcomes of members/patients.

The result is substantially lower prescription drug spending, in particular specialty medications.
Lowering Specialty Drug Costs Through Clinically-Driven Pharmacy Care
BETTER PRESCRIBING = BETTER ADHERENCE
Patient: 60-year-old-female
Diagnosis: Osteoporosis
Original Rx: Forteo 20mcg daily injection
Population Health Management Engine Identified: Review for clinical appropriateness.
Clinical Pharmacist reviewed the request for Forteo injection and suggested a first line oral medication, due to the patient’s fear of needles and Forteo requiring daily injections. The prescriber agreed to switch the patient to an oral medication, Alendronate, which has resulted in optimal outcomes and ensured adherence to therapy.

  • New Therapy: Alendronate 70mg tablet by mouth taken once weekly
  • Outcome: The patient has remained adherent to treatment with Alendronate leading to positive clinical results
  • $41,608 Annual Plan Savings achieved
TREATING THE PATIENT NOT JUST THE CONDITION
Patient: 63-year-old male
Diagnosis: Lung adenocarcinoma
Original Rx: Tagrisso 40mg twice a day 
Population Health Management Engine Identified: Review for clinical appropriateness
After detailed review of clinical chart notes, our Clinical pharmacist identified that the prescribed dosage could exacerbate the patient’s existing cardiomyopathy, which could be life-threatening. Based on clinical guidelines, the Pharmacist recommended a lower dose to reduce the risk of patient’s cardiomyopathy worsening.

  • New Therapy: Tagrisso 40mg once a day
  • Outcome: The patient continued treatment without worsening of the existing cardiomyopathy.
  • $15,695 Annual Plan Savings achieved

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